Karen Holthaus (nee Bill), devoted mother of Nick Holthaus, Charlie (Corey) Holthaus and Katie (Nick) Luberger. Loving grandmother of Elliot and Josephine. Dear sister of Don (Kris) Bill, Judy (Gary) Benke, Lorie (Mike) Turner and the late Joe Bill. Daughter of the late Albert and Loraine Bill (nee Gener). Karen passed away on Friday, March 19, 2021 at the age of 62. Mass of Christian Burial at St. James Church (White Oak), 3565 Hubble Rd., on Friday (March 26) at 11:30 a.m. Funeral mass will be lived streamed at https://www.stjameswhiteoak.com . In lieu of flowers, memorials may be made to Bluegrass Hospice, 7388 Turfway Rd., Florence, KY 41042. Special condolences may be expressed at www.frederickfh.com